Andrew struggles to blend in after a growth spurt, Nick worries his hormones are out of whack, and Jessi and Jay get a taste of the teen runaway life.

A classmate's booming bosom sends the boys into a rapture -- and leaves the girls with a raging case of insecurity. Coach Steve drops a bombshell.

As Nick tries to figure out whether he has a shot with Gina, a mortifying encounter with Leah sends Andrew into a spiral of shame.

Coach Steve finally gets his chance to do sex on a lady, Nick and Andrew go on a double date, and Jessi's rebellious streak leads to big trouble.

An argument in sex ed class turns into a skit-tastic journey through the worlds of Planned Parenthood, contraceptives and STDs.

Jessi and Nick dip into her dad's stash of edibles, with mind-bending results. Andrew searches for the right moment to break up with Lola.

While helping Greg move into a seedy bachelor complex, the boys and their dads debate what women want -- and what it means to be a man.

A school sleepover turns messy as Nick dishes on a makeout session and the Shame Wizard works his miserable magic on the whole class.

Nick tries to lighten the mood at the sleepover with a new twist on Truth or Dare. The Shame Wizard meets his match. Jessi vows to change her ways.

After traveling through a magic portal to puberty headquarters, Nick seeks out a new Hormone Monster and Jessi bonds with the Depression Kitty.

Sappy cards. Stupid clichés. And so much pressure. For Andrew, Nick, Jessi and friends, Valentine's Day is a total freaking minefield.

When a shop class mishap inspires a sexist dress code, Jessi rebels, Missy struggles to keep her alter ego in check, and Andrew gets a wake-up call.

Nick is bewitched by his cool new phone. A call from "Pharmacy Boy" turns Matthew into a nervous wreck. Jay finds a Netflix show made just for him.

Cellsea goads Nick into posting a risqué video, Maury urges Matthew to speed things up with Aiden, and Jay feeds Missy ideas for her erotic fiction.

While Nick tags along with the Gloubermans on a wild road trip to Florida, Jay discovers he's been "Home Alone'd" -- and moves in with a new family.

Connie gives Jessi a crash course in female pleasure, Maury tries to talk Andrew into sending a dick pic, and Nick lashes out at his new housemate.

The ghost of Duke Ellington takes Nick and friends on a journey back in time to 1913: the year he lost his virginity and found his true calling.

As the friends feverishly swap lists of the hottest kids at school, newcomer Ali stokes the flames by announcing she's pansexual.

A big standardized test sends everyone into a panic -- except for Jay, who just scored an Adderall prescription.

A provocative school musical unleashes Missy's inner thespian -- and her new Hormone Monstress. The "Queer Eye" Fab Five pay a visit to Coach Steve.

When a freak storm gives everyone new superpowers, tensions between Andrew, Nick and friends boil over into an epic showdown.

At sleep-away camp, Jessi befriends her trans cabinmate, and Nick discovers his two best friends have a little too much in common.

While Jessi deals with menstrual mayhem, Nick tries to avoid showering with the guys, and Missy gets a makeover from her cousins in Atlanta.

On the last night of camp, bowel problems, a talent show and a hookup lead to hurt feelings. Back home, Jay and Lola throw a pool party.

After seeing their eighth grade classmates coupled up, Nick and Andrew make a play for two seventh grade girls. Jessi adjusts to life in the city.

On a trip to the 9/11 museum, Nick and Andrew sneak off to meet Jessi, Devon teaches Missy about code-switching, and Coach Steve gets a rude surprise.

Thirty years in the future, rich but lonely game show host Nick prepares to flee a dying Earth. But first, he has to track down the perfect plus-one.

The kids at Bridgeton Middle explore enthusiastic consent, feminine pleasure, coercion and more in four short films.

Wracked with guilt, Andrew tries to keep his urges in check. Matthew's mom ices him out of the church bake=off after reading his texts.

A trippy haunted house hosted by Kappa Kappa Kill forces each of the friends to reckon with their biggest fears.

Forced out of his own body by his smug alter ego, Nick fights back - with help from his friends and Gratitoad. Matthew comes out to his dad.

To get his mind off Lola, Jay begs his pals to join him in a monthlong challenge. Missy's caught off guard by a new crush.

Eager to get his mojo back, the Shame Wizard drops in on swim class to torment the kids with bodily insecurities.

As Walter the love bug coaches Nick on matters of the heart, Jesse gets fired up about protesting the school's problematic mascot.

Unrequited love and jealous rivalries turn the friends into seething beasts. Andrew gets a little too invested in a substitute teacher.

Missy tries to show her cousins she's not a dork, Andrew takes a stand against his dad's turkey tyranny, and Jesse hopes for a Thanksgiving miracle.

While Jessi sorts through her feelings for Ali, Nick joins Devon for a boys' night, Andrew shows off his new persona, and Missy starts a rumor online.

Emboldened by their new monsters, Missy and Nick descend into a hate spiral. Meanwhile, Jay puts on a big show to win back Lola.

Classic holiday stories get a naughty makeover in this special episode hosted by puppet versions of Maury and Connie.

On a Birch family ski trip, Leah prepares to go all the way with Val, and Andrew hits it off with a fellow ski noob. Matthew helps Jay out of a slump.

Nick follows Walter to the land of monsters and demands to see the person in charge. A New Year's Eve party inspires a flurry of grand gestures.

After being snowed in with their families, the restless friends flock to Bridgeton's latest make-out spot. A new classmate catches Missy's eye.

A DNA test leads Nick to uncover a wee family secret. Jay insists on introducing Matthew to the Bilzerian clan. Andrew puts his lovebug to the test.

From itching to grooming to late blooming: There's no shortage of fodder for shame maven Rita St. Swithens in this special episode.

A viral quiz about naughty deeds sparks arguments and unlikely new friendships. Matthew plans a baby shower for Maury.

While Andrew prepares for a momentous evening with Bernie, Nick sets out to meet his secret grandfather, and Jay cooks up some romance for Matthew.

The voice of a slick, new tech accessory hypnotizes people into doing things they wouldn't normally do. Missy grapples with the concept of sin.

Lola hits the jackpot — in more ways than one. Missy takes her dad to Elijah's church. The Birches make a plan to get rid of their new housemate.

Elijah tries to figure out why he doesn't have the same urges as his friends. A jealous Andrew hops a train to Vermont to surprise Bernie

While Andrew and Nick deal with parental crises, Jessi meets her new sibling, and Matthew realizes he's made Jay into a different person.

A sudden outbreak of body-swapping yields awkward situations and poignant revelations galore.

With two months left in eighth grade, the incoming freshmen tour their new high school with junior hosts while Jay evades his terrifying brothers.

A doctor puts Andrew on testicular rest, Nick asks Jay to help him get in shape for high school and Jessi becomes fascinated by Caitlin's breastfeeding.

With no distractions, Andrew's schoolwork improves — winning his father's praise. Jessi goes a little too far when trying to emulate cool, mature Leah.

While Andrew and Nick follow Judd to Brooklyn to score drugs, Jay gets jealous of Kurt and Lola's relationship, and Jessi oversteps at Matthew's house.

As graduation day nears, Nick must decide if he will attend Cobblestones Academy while Andrew goes on an apology tour after being voted "Grossest Human."

Big Mouth goes global for a very special episode as Maury and Connie take a closer look at how kids around the world experience puberty.

Andrew takes a liking to his new neighbor — and her mom. Nick wants to be more than Danni's friend, but her entanglement with Travis gets in the way.

At their first high school party, Andrew discovers his talent for drinking games, Nick hopes for a shot with Danni, and Missy meets a potential rebound.

During a sleepover, Jay teaches Andrew how to defend himself against bullies. Then, Missy gets overwhelmed while back-to-school shopping with Jessi.

The Big Mouth kids start high school! Andrew looks inside himself to solve his problem with Pumbaa while dread stops Missy from attending her first day.

With a big dance approaching, FOMO's everywhere: Missy misses school, Matthew dives into the deep end — and Andrew suspects that Other Andrew is evil.

Jessi and Jay pair up to parent a melon "baby," Missy faces her fears, and Nick and Other Andrew try to fit in with a group of ultra-rich kids.

After Nick has a sudden growth spurt, Ms. Dunn takes the class inside the body of a teenager to learn about the wonders of puberty.

A reckless Lola gets behind the wheel, and Jessi and her mom have a really big fight. Nick's mother finds his "special shirt" while cleaning his room.

Depression Kitty convinces an anxious Jessi to care less. Nick attracts Devin's attention, and the Robotics Club takes an overnight field trip.

Matthew explores his sexual preferences, Nick says the wrong thing, and Missy uses Andrew to make Nate jealous. Jessi finds a surprise on Camden's phone.

Connie recruits a Compassion Pachyderm to teach the kids how to see things from another point of view. Andrew sets out to steal Missy's man.

Missy's Lovebug steps in to solve a problem, and Jessi practices enthusiastic consent. Nick tries life without porn. Lola gives Jay's dog a makeover.

In honor of the show's next-to-last episode, Maury and Connie dive into the "Big Mouth" mailbag to answer curious fans' burning questions.

As the kids creep closer to adulthood, a memorable finale takes them back to where it all began to say goodbye — and face the future.