Student Peter Parker is labeled a "bookworm" by his peers when he declines their offer of a triple-date in favor of viewing a radiology experiment.

On his first night at work at the Daily Bugle, Peter overhears talk of a fake medicine racket engineered by a rotund mobster called the Kingpin.

A twisted radiation specialist gains illicit dominion over Manhattan's new and only nuclear power plant and uses a special ray to lift Manhattan into the clouds.

Roy Robinson, star football player, campus ladies' man, son of a wealthy chemical industrialist, is envied by Peter, who decides to use his spider-power to play football and outperform Robinson.

Investigating the disappearance of banks, Spidey finds a hole that leads to a maze of underground tunnels, through which Spidey undertakes a perilous journey in search of the lost occupants of the submerged banks.

A baseball diamond and the spherical, baseball-sized Optimo Diamond at the Cosmopolitan Museum are connected in this episode.

Mugs Riley, evidently escaped from prison, has duped the Molemen into following him again.

Giant, mechanical beetles are used by Manta to capture and enslave the peace-loving inhabitants of an island to mine a valuable ore.

In ancient Egypt, one of the most aggressive of evil magicians, Kotep, the Scarlet Sorcerer, is defeated in battle with an opponent, and his own demons strike him with a cursing ball of fire that puts him in suspended animation, his mummified remains lasting through the passing centuries and becoming an exhibit at a New York university and the object of a professor's obsession.

A giant plant escapes from storage in a house belonging to Prof. Smithers, a missing scientist. Spidey goes through a portal (located in the scientist's home) to prehistoric times to find some defense against the plant and meets Smithers, who tells to him that two radium gems in an idol in a nearby city, if ingested by the plant in New York, will disintegrate it.

Pardo is a sorcerer with the ability to transform himself into a giant cat with hypnotic eyes. He lures top New York City’s citizens and officials to a theatre with the promise of a spectacular show, then releases his feline alter-ego's power upon the hapless audience, intending to divest them of their wealth and sap the souls out of their bodies.

Peter is an exchange student in South America, flying in a charter airplane with a Latin American professor in the Andes mountains. The airplane encounters a violent storm and crashes in a jungle, and Peter changes to Spider-Man to assist the professor and the airplane's two pilots in leaving the jungle and returning to civilization.

On Jameson's orders, Peter, and Daily Bugle pilot, Penny Jones travel by small-engine airplane to the Antarctic Ocean to track a fallen nose cone and crash-land on an island with a superstitious, brutish, native population.

At a coffee house, Peter meets Carol, a girl with whom he has much in common; he does not realize to what extent that they are alike until he, as Spider-Man, catches Carol in the act of robbing electrical equipment and finds that she has powers identical to his.

Clive, an unbalanced movie producer, is determined to avenge himself upon critics and audiences who spurned his claim that the darkest human emotions could be filmed and physically released from a theatre screen.

A giant Martian warrior, who throws lightning bolts, comes to Earth to rob the planet of its gold.

Dr. Irving Caldwell has devised a helmet capable of levitating its wearer and is kidnaped by a villainous scientist, Dr. Zap, who wants Caldwell's helmet to duplicate for his own evil use.

Sophisticated diamond thief Dr. Cool and his henchman have heisted a fortune in diamonds and are at a deserted-before-dawn ice factory, planning to smuggle the gems through international customs by mixing the "hot ice" with large quantities of the ordinary variety.

Two robbers dynamite a bank safe and abscond in their car with millions of stolen dollars.

Spidey discovers the bird-man Vulture robbing a millionaire's penthouse safe and unsuccessfully tries to stop the flying fiend.

Spidey swings to Florida again to battle a walking, thinking lizard. This time, the lizard is not a transformed Dr. Conner, but a reptile whose intelligence has been augmented in an experiment by Conner gone awry, and who has kidnaped Conner and holds the ill-fated scientist as captive at a Spanish fort.

New York City children build a snowman with snow contaminated by trace chemicals from an industrial plant up the Hudson River, and a freak accident involving a broken electrical line hitting the snowman somehow brings the snowman to life.

Desperado, a cowboy criminal, lassos Spidey and begins a crime wave atop his electronic horse.

A German Baron utilizes a flying aircraft carrier to launch an attack on New York City with World War One-style fighter airplanes.

The Kingpin's latest scheme to control New York involves a machine that brainwashes city officials into doing as the commands.

Dr. Vespasian, a green-skinned, wrinkled scientist, concocts a drinkable invisibility formula and uses it on himself and his dog, Brutus.

From his vantage point atop a building, Spidey watches as crowds form long lines to attend Saturday night Broadway performances. To the panic of the mass of people, the Moon becomes a psychedelic pinwheel that fills the night sky and dizzies and renders everyone- including Spidey- unconscious.

Super Swami, an obese illusionist, seems to make the Brooklyn Bridge disappear piece by piece.

Professor Pretories, the most diabolical mind ever known to science, escapes jail, and Peter unknowingly helps the convict by car-driving him, a hitchhiker, to his secret-laboratory hideout.

Spidey jousts with a motorcycle-riding knight in armor who is robbing theatre box offices, armored trucks, and museum officials receiving a medieval artifact.

Dr. Dumpty, a corpulent jewel thief, attacks a parade with knock-out gas released from balloons, and he and his thugs, wearing gas masks, steal the jewels of actress Rachele Wells and abscond in a hot air balloon.

The weird Dr. Atlantian rises out of the ocean near New York City in his hive-like machine, which derives its power from Lunar motion.

A remake of Season 2's "Vine", virtually identical in plot; the only difference is that instead of a giant plant threatening New York, the menace is a series of enormous, rolling pods that grow from boxes in a missing scientist's house.

In a cheater story comprised of footage from both Rhino episodes from Season 1, the Rhino again steals gold shipments with which to build a 14 karat statue of himself.

Spider-Man tussles once more with master-of-illusion Mysterio. This time, Mysterio causes Spidey to think that he has shrunk the web-swinger and placed him in a miniature amusement park.

Luck, Suggestion and Determination must guide Spider-Man through this trip into the 5th dimension. Spider-Man finds himself face to face with The Skeletal Infinata.

An old enemy of Spidey's, a radiation specialist who once lifted Manhattan into the sky, has been released from jail and promptly revisits Manhattan's nuclear power plant, stuns the outdoor guards with his ray gun, and again commandeers the reactor.

Jameson orders Peter to fly in an airplane with Daily Bugle pilot Osa Olsen to the North Pole to locate a fallen meteor with bizarre antennae, but a thunder-snowstorm cripples Parker and Olsen's airplane, and it crashes in a wasteland populated by a tribe of savages.

A bolt of lightning breaks Spidey's web, causing him to fall into a boxcar at a rail yard. In the boxcar, Spidey meets a young runaway who plans to ride a freight train out of New York City and become "the Caped Protector of Podunk".