650-lb Melissa begins her seven-year weight loss journey.

650-lb Melissa struggles to get to her ideal weight.

Love motivates 660-lb Donald to begin his weight loss journey.

750-lb Henry begins his weight loss journey in the hopes of transforming himself in time to attend his high school reunion.

Ashley's career was derailed after she was let go due to her excessive weight. Will she be able to turn her life around and achieve her goal of owning a childcare facility?

Zsaylnn, once known as the "Fat Girl Rock Star" - married a man who loves large women. Now weighing over 600lbs, she urgently needs to lose weight to be the mother her daughter deserves. Can Zsalynn succeed with a husband who doesn’t support her goals?

Battling severe depression in the wake of a suicide attempt, 46-year old Olivia hasn't left her Chicago basement in two years. With one last chance at a new life, Olivia will travel to Houston with the hope of having a life-changing surgery.

Bedridden for four years, 46-year old Penny knows that her weight may kill her if drastic actions aren't taken. Penny moves from Maryland to Texas, to have gastric bypass - but her unwillingness to make real lifestyle changes could be her downfall.

Chuck weighs almost 700lbs and it has hindered every aspect of his life. He's had to downsize his business and his wife feels like a single-parent, who is ready to leave him. Can Chuck take control and reclaim the life that's slipping through his fingers?

Christina is a 22-year old married woman from South Haven, Mississippi, who hasn't left her house in two years due to her size. Her doting family has enabled her and she's eaten herself into a state that will soon kill her, if she can't make a change.

Paula has had a tough life, and at over 600lbs, has built a physical wall around herself to push people away. When she suddenly loses someone she loves, Paula can no longer ignore the threat of losing her own life - especially for her children's sake.

James comes from a long line of family obesity and at 706lbs, is determined not to die in the same hospital bed that his father and sister did. James vows to change his lifestyle in order to get gastric bypass, and even has hopes of dating again.

Tara is a mother of two from Lafayette, LA. Addicted to food, she is too ashamed of her size to be seen with her kids, confining herself indoors. Now seeking gastric bypass, Tara is committed to regaining her confidence and being a proud mother once more.

At age 23, and over 600-lbs, Amber relies on her family, and boyfriend for even simple needs. Her fear of dying young is so overwhelming that she makes the decision to relocate 2,000 miles in hopes that weight loss surgery will give her life back.

Weighing in at over 600-lbs, 37 year old Susan is committed to drastic weight loss. But, when an unforeseen medical disorder strikes her mobility, finding the strength to make it through these obstacles is a matter of life and death.

At nearly 700 lbs., 51-year-old Pauline has an addiction to food that is killing her and taken over the life of her son, who is the primary caretaker. Can she overcome this addiction to change her lifestyle and save both their lives?

At just 24, Bettie Jo is eating her way towards 700-lbs. Housebound, she is reliant on her husband for even basic needs. Bettie Jo's future relies on her losing weight, and her husband losing his fear that if she loses weight, she will leave him.

At 42 years old, Angel is staring death in the face. She is struggling to make a positive change and be an active part of her partner and son's lives. With so much at stake, can she turn her life around?

Joe is only 30, and trapped in an 800-lb body. He lost his job and is mostly housebound. Can Joe find the strength to face his past and save his life?

Laura has used food to cope with her emotions for too long. Confined to a wheelchair, relying on an oxygen tank to breathe, she depends upon her husband and mother to survive. Love for her family must conquer her demons if she is to turn her life around.

Charity weighs nearly 800-lbs. Suffering from flesh-eating bacteria and butterfly shaped fat deposits; she is unable to function without help form her family. When unexpected bad news threatens her weight loss journey, she must decide if she can continue.

Chay is just 23, but to cope with the emotional turmoil of his childhood he has eaten his way to 600-lbs and it's threatening to kill him before turning 30. When Chay loses his emotional support, he must find new strength to take control of his life.

Marla is so heavy she cannot stand up. Bedridden, her true weight is unknown but estimated at 800-lbs. Marla must face the facts about her health and the toll it takes on her supportive family if she is to save her health.

Nikki's life and career are threatened by her 650-pound weight. Determined to make a change, she undergoes weight-loss surgery.

Brittani has reached almost 600 pounds at just 32 years old. Though her husband loves large women, she lives in constant pain and hides her body from him for fear of rejection. In hopes of better health and a better marriage, she undergoes weight-loss surgery.

At over 700 pounds, Chad's weight is out of control and gastric bypass surgery is his last resort. He sells his house to be able to afford the surgery, but his recovery is complicated when he faces a medical crisis and fails to follow doctor's orders.

June, at almost 600 pounds, has coped with the tragic death of her son by eating. Confined to her house and unable to care for her three children, she must make a change and pursues gastric bypass surgery. Her girlfriend and primary caretaker Sadi supports her efforts.

At over 600 pounds, Dottie agrees to a drastic new diet and gastric bypass surgery in hopes of reclaiming her health and ability to care for her children. Her child's life-threatening emergency and her own self-sabotage threaten to derail her efforts.

At over 600 pounds, Gideon's is unable to work and completely dependent on his exhausted wife. Fearing an early demise and desperate for change, he uproots his family to undergo weight-loss surgery in hopes of reclaiming his life and health.

Ashley is just 26 years old and over 700 pounds. Her 5-year-old son is one of her primary caregivers and a motivating factor in making a major change. Knowing her life is on the line, she pursues weight loss surgery but faces medical setbacks and various struggles in the process.

At over 700 pounds, Teretha's life is confined to a bed -- a far cry from her former job representing Detroit's healthy eating program. Her adoring family fears losing her and hopes bariatric surgery will help save her life.

At 650 pounds, Randy's weight has led to the loss of his marriage and custody of his daughter. In a last ditch effort to save his life, he begins a rigorous diet to undergo weight loss surgery. He battles the temptation of fast food, as well as lingering depression, and struggles to keep his job.

At about 700 pounds, Milla is bedridden and unable to feed or bathe herself -- her five children care for her every need. She knows she must make a change for their sake as well as hers and in an attempt to reclaim her health, she moves to Texas to undergo weight-loss surgery.

Sean weighs almost 1,000 pounds at just 26 years old. His skin is so stretched it is tearing apart, and a massive growth protrudes from his side. With the support of his mother, he attempts weight-loss surgery to save his life.

Lupe, at almost 600 pounds, has been bedridden for 10 years and depends on her husband for all her needs. A cross-country move to Texas for weight-loss surgery is her last chance for change, but it may be too late.

Twins Kandi & Brandi have a combined weight totaling over 1100lbs. These inseparable twins fear losing each other to obesity, so they make a change together. But a life-threatening event during weight loss surgery recovery may separate them forever.

At 670 pounds Ashley must live in her parents' home with her husband. Desperate to save her life and her marriage, she decides it's time for a drastic change. Can weight loss surgery save her life?

Cynthia is a 610-lb single mother raising five kids. She's been focused on her children, but now realizes what her death would mean for them. As she battles her emotions & the pressures of life, she is forced to fight harder to save her own life.

Weighing over 600-lbs Kirsten is close to losing her mobility. While she's trying to get control of her obesity she's also in danger of losing her troubled son. She must regain her health in order to be the best mother she can to care for her son.

After overcoming a dependence on drugs & alcohol, sneaking food is 660-lb Doug's last remaining vice. Can this husband, and father of 3 overcome his addictive personality and take control of his eating habits in order to save his life & his marriage?

At 661 lbs, Erica regrets not keeping a promise to her mom. She hopes her siblings will help but they are reluctant based on past failures. Each meal threatens Erica's worst fear coming true; dying the same way she lives, alone & surrounded by food.

Diana, a once thin & active woman, is now a prisoner to her 620lb body. Desperate to break free of her food addiction, she trades the comfort of her home for a weight loss journey under the strict authority of her niece in order to regain her life.

Michael's massive 632lb body has left him completely dependent upon his family. If he doesn't learn to control his anger issues around food, lose weight, and address the root of his issues, then he will remain in jeopardy of losing everything.

Weighing over 700-lbs, Nicole is on the verge of leaving her two young children motherless. Trying to survive a family of addicts, she commits to Dr Nowzaradan's diet program, but crisis threatens to derail all her hopes for weight-loss.

Tanisha weighs around 600-lbs and she's desperate to survive for her kids and avoid her mother's tragic fate of dying at age 50 from super obesity. Now at 32, her future looks grim if she doesn't make a drastic change to save her life.

Weighing 791-lbs, James is bedridden, unable to stand, and can barely move his legs. He may only have a few months to live, so his family takes a high-risk journey to Houston, Texas, with the hope that bypass surgery can save his life.

Most of the extreme weight on Tracey's body resides in her shockingly misshapen legs. They're so massive with severe lymphedema, that gastric surgery is her only chance of survival. Will this mother & grandmother ever gain control of her overeating?

Steven Assanti weighs nearly 800-lbs and his brother/nemesis, Justin, is almost 600-lbs. Though the brothers can't stand each other, their father packs up the family to travel across the country to seek help, desperate to save both his sons' lives.

After a year on a weight loss program, Steven remains completely non-compliant, and Justin focuses on a new career instead of his diet. With neither brother close to being approved for life-saving surgery, time is quickly running out for them.

Dr. Nowzaradan is worried Lupe's emotional issues are blocking her weight loss journey since she's shed over 300 lbs. but still can't walk. Ashley is struck with sudden paralysis. Sarah and Roger prepare for skin removal surgery.

Brittani will have to endure two more painful surgeries to achieve her ideal body. Will Sean finally make a break from his mother's over-protective care? And Annette and Calisto prepare for skin removal surgery.

Surgery enables Teretha to finally return to family in Detroit, but it soon threatens to undo all the progress she's made. After his weight loss surgery, trucker Chad gets back on the road, but the job is putting any further weight loss in peril.

After losing 250 lbs, Nikki is on her way to skin surgery that will transform her body. But when a close friend dies from weight loss surgery, Nikki's progress goes off track. And Mary and Lora prepare for skin removal surgery.

A woman's weight-loss journey is in danger of going off track following the sudden loss of her son; a woman embarks on a plan to win approval for skin surgery.

Charity manages to lose over 400 pounds, but her daughter Charly becomes dangerously obese. Devastated by the death of her husband, Elroy, Milla must find a way to finally qualify for gastric bypass.

A man who weighed 800 pounds is engaged, but must continue to lose weight; a woman is on the verge of independence if she qualifies for skin surgery.

Surgery enabled Laura's independence but the complications nearly killed her and she's terrified about the next skin surgery. Chay revealed to her family she was transgender but living life as an overweight woman; can she stick to her weight loss journey?

After meeting and falling in love at a bariatric rehab center, Lee and Rena are battling health and anger issues while making a desperate, second attempt to save their lives.

A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again.

A devoted girlfriend and loving aunt, Alicia is all smiles and laughter on the outside, but on the inside she is terrified that her addiction to food will kill her before she can marry her long-time love or watch her nieces grow up.

A woman with two children weighs more than 600 pounds, so she agrees to go on an extreme new diet, but her weight-loss efforts are threatened by her debilitating habits and a child’s health emergency.

James LB Bonner spent his early life trying to prove himself to his adoptive family, but after losing a leg and battling obesity, LB must take a new path to save his health and his family relationships.

Lisa's struggle with her weight begins as a child and significantly worsens after witnessing her brother's murder; now bedridden and unable to care for herself, she must lose the weight or she will never see her grandchildren grow up.

Now bedridden and unable to care for herself, Lisa must find a way to lose the weight or she will never see her grandchildren grow up.

After years of a tumultuous relationship with her husband, Tamy's eating addiction causes her weight to balloon over 500 pounds; she becomes a hermit after years of shame and hopes to restart her life so she can better care for her son, Zachary.

Fearing that he'll suffer the same fate as older brother David, now 700 pounds and unable to work, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey.

A former plus-size model and "big is beautiful" advocate, Renee realizes the mortal mistakes she made as her weight swells to 600 pounds and her health crumbles.

A 24-year-old woman weighs more than 600 pounds and is fighting for her life after a difficult childhood with an abusive stepfather and drug-addicted mother.

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight loss surgery will be able to fix her fertility issues as well as her marriage.

Jennifer and her daughter, Marissa, are stuck in a co-dependent relationship that puts both of their lives in jeopardy, with a combined weight of more than 900 pounds; Jennifer strives to regain control before it's too late.

A 400-lb. woman learns that she's pregnant, but wonders if she'll be able to deliver the baby without complications; a woman who lost 400 pounds is in a relationship, but it could be in jeopardy when her weight-loss journey stalls.

Melissa has lost 500 pounds and saw her weight drop to 137 pounds, but now faces marital problems and life as a single mom, all while struggling with a gain of 150 pounds.

Back on Dr. Nowzaradan's program, James is suspected of cheating as he continues to gain weight and suffers a series of life-threatening illnesses. Cynthia continues to lose weight but seems satisfied to do so at her own pace.

Back on Dr. Nowzaradan's program, James is suspected of cheating as he continues to gain weight and suffers a series of life-threatening illnesses; Cynthia continues to lose weight but seems satisfied to do so at her own pace.

Losing over 200 pounds, Doug is now an active part of his family's lives and inspires a healthier lifestyle for them all. However, Doug's eating disorder and trouble finding his own identity threaten to derail his progress.

Ashley hits an emotional wall and is desperate for skin surgery, but she is not losing any weight. After being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.

Brittani has lost over 400 lbs. in two years. As part of her next chapter, will she and Bill start to plan to expand their family? Lupe has struggled since surgery. Having left her husband, will she finally start to make permanent changes she needs?

Octavia has been bedbound for nearly a year when she decides to make the trip to Houston to get help from Dr. Now, but when it turns out that her best friend is also her worst enabler, Octavia will have to choose between old habits and a new life.

At over 700 pounds, Brianne undertakes a weight-loss journey to save her own life; she faces an unexpected challenge to her fragile progress when her husband suffers a heart attack on a birthday she will never forget.

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can't go; Chris' son Garrett, already 600 pounds at age 20, is game to join the journey.

A college graduate with a once-promising career, Justin has eaten his life away to the point of never leaving the house for anything but food; only the help of Dr. Now's weight-loss program can restore his hopes of living a happy, productive life.

Holly already has one failed weight loss surgery, so to succeed this time, she must do more than change her eating habits, she must address the childhood issues that continue to plague her.

Lacey ballooned up over 600 lbs on pizza and ice cream and knows Dr. Now is her best hope for success; she must now rally her divorced parents around her for support and find a way to modulate her moods that won't include binge-eating.

Brandon is a talented musician with a beautiful voice and a run-away weight problem; he wants to lose weight and embark on a career; he also wants to take the next step with his girlfriend, Taylor, whom he risks losing if he can't make a change.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

Despite moving to Houston with the solid support of her boyfriend, Aaron, and her cousin, Jasmine, Tiffany finds it difficult to break the cycle of depressed eating when her two roommates don't join her diet and leave the house every day for work.

Born as "Matthew," Destinee never felt like she fit in; now, having come out as a 600-pound transgender woman, she likes her curves, but she will need to say goodbye to them if she wants to be approved to transition completely.

Jeanne lives in an unhygienic household with her mother and schizophrenic father; at well over 600 pounds, Jeanne might never get weight-loss surgery as she runs into several obstacles, especially after an unexpected death in her family.

Since the death of his mother, Aaron lives at home to care for his aging father, but due to his food addiction, Aaron has to heavily rely on his father for help instead; Aaron must learn to care for himself to avoid eating himself to death.

Kelly is on the verge of immobility when she decided to make the trip to Houston to visit Dr. Now; Her journey gets off to a painful start when a long travel day grows longer as Kelly gets stuck in a cab on her way from the clinic to the hospital.

When Annjeanette was nine, a campaign was established to send her to fat camp; she hated that her weight had become a source of public shame and she has struggled to overcome her food addiction; now, she must change her habits to save her life.

When Annjeannette was 9, a campaign was established to send her to fat camp. She hated that her weight had become a source of public shame and she has struggled to overcome her food addiction. Now, she must change her habits to save her life.

A mother of 4, bed-bound for 2 years, Lashanta relies on her kids to keep her cleaned and fed. Her last chance to break the cycle of food addiction that's killing her is to join Dr. Now's program, but it will take a village just to get her out the door.

Cillas' food addiction is getting in the way of his ability to be there for his fiancée, Jessica, and her three daughters; if he doesn't lose weight soon, he knows he'll lose either his girls or his life.

Mercedes, who has severe lymphedema, must overcome trauma to lose weight.

At over 600 pounds, Angie is trying to get to Houston to see Dr. Nowzaradan, in hope of getting weight loss surgery to save her life; family conflict and disagreements may stop her from being able to do what she needs before she even gets the chance.

Weighing over 600 lbs. each, Vianey and Allen are locked in a codependent relationship based on a shared love of food. As they head to Houston, they will soon find out if their relationship can handle the strain of growing healthy together.

As Steven heals from his weight loss surgery, his brother Justin finally decides to come to Texas to get the same procedure, but his feelings toward Steven immediately begin to sabotage his hopes of surgery.

A year since her weight loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat her if she can't find a way to control her eating habit and start walking again.

Lee's anger issues continue to jeopardize his relationship with Rena and threatens to derail both of their weight loss journeys; a major life event sends Sarah into a depression that she must pull herself out of if she wants to keep losing weight.

In the fourth year of his weight-loss journey, Sean struggles to get past the loss of his mother and live on his own; Dr. Now intervenes to control Sean's eating for a time.

Liz has gone from being bedbound with lymphedemas on both legs, to standing and walking, but old fears are about to threaten her progress; if Jenn and Marissa can't get along as mother and daughter to lose weight, they'll have to proceed apart.

For Milla Clark, after 3 years and 5 surgeries, success would mean beating the odds, and becoming of on Dr. Nowzaradan's most impressive weight-loss patients ever, but failure would mean slipping back to the bed-bound life she swore she'd never return to.

Pauline's self-destructive behavior continues to be a problem; Chad strives to be a better father and husband as he continues his journey; June's progress stalls when frequent travel and wedding plans cause her to slip back into bad habits.

John & Lonnie are two brothers from opposite ends of the spectrum. For years estranged, the brothers are now brought together by a common need to lose weight while they still can.

Lindsey has a white picket fence, a loving husband and a great job, but her food addiction threatens to ruin everything; as she embarks on a weight loss journey to save her life, her husband may provide more harm than support.

Bethany has two daughters who live in fear of losing their mom to her food addiction. Once an addiction counselor, Bethany has gotten so big that she can no longer work. Now she risks losing her life if Dr. Now can't help her curb her own addiction.

J.T. is almost 900lbs with a 100-lb lymphedema mass on his leg and a food addiction that is bound to kill him if he doesn't change. His girlfriend takes him to Houston, but when his behavior drives her away, J.T. is left with only Dr. Now to help.

When Travis got too big to walk down the aisle, he promised to give his wife a proper wedding one day. Since then he's only gained weight. Now, Dr. Now is Travis's only hope to lose weight and get the life he and his wife dreamed of having together.

Joyce needs home health care 24/7 and hasn't left the house in years. But getting to Dr. Now in Houston is just the first step, and when he prescribes therapy where Joyce must revisit an unhappy past with her mom, it may be more than she can handle.

Shantel's brother Carlton lives downstairs but she hardly ever sees him because at 600+ lbs each, neither can do the stairs safely. They need Dr. Now's help to break free from a death spiral of codependent eating & reforge their sibling relationship.

Seana is 23 and nearly 700 lbs, living at her mom's house, depressed and anxious, her weight-gain threatening to take her last breath. Dr. Now can give her the tools she needs to live, but until she chooses life, no one can save Seana but Seana.

At 600 pounds, Ashley has to move home so her mom can help her care for herself and her newborn daughter; Ashley must overcome a lifetime’s worth of unfortunate circumstances and get Dr. Now’s help in Houston.

Tommy wants to lose weight so he can marry his fiancee and have the life he always dreamed of, but to break the cycle of pathological eating, he’ll have to face a piece of his past he has always kept secret.

The four best reasons for Coliesa to live are her daughters. But after a heart attack and losing the love of her life in a car crash, Coliesa eats non-stop to escape from reality, and ... See full summary »

Dominic's life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only Dr. Now can help him learn to face life's challenges without using food to cope.

At 24 years old and over 600 lbs, Megan lives at home with her mom, who cooks for her since Megan can't do much on her own; Megan must travel to Houston to meet Dr Now and change her eating habit or her life may end before it ever begins.

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley learns that Dr Now isn't someone she can lie to like her online friends.

At nearly 1,000 pounds, Samantha is dangerously close to dying. To make matters worse, she's paid to eat by making videos online. If Samantha doesn't overcome her toxic relationship with food, she worries that she will leave her daughter motherless.

Thederick has become housebound from eating, and for 10 years, he's only gone outside to greet the ice cream man. After a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.

20 years after her dad died as a result of a botched weight loss surgery, Carrie is on the brink of eating herself to death. To live, she must face the fear and grief of losing her father and end a cycle of toxic behavior with her husband Chris.

Cindy is resistant to change and has spent years creating a world that makes her feel safe. When her friend notices Cindy's health declining rapidly due to her size, she pushes Cindy to move to Houston and see Dr. Now. But Cindy isn't so easily persuaded.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body. Now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Kenae' was already big before her weight gain took off after the death of her beloved mother. Refusing to deal with the pain, Kenae' turned to food to fill the void. But she'll be reunited with her mom soon if the denial continues.

Krystal began overeating to shield herself with a protective layer of obesity after suffering years of abuse. Once a means of protection, her pathological eating now threatens to destroy her life if she doesn't get help.

Isaac helped raise his siblings after his mom suffered a debilitating stroke when he was 10. While learning to cook for his family, he began comfort-eating. Now to avoid eating himself to death, Isaac must learn to take care of himself for a change.

A lifetime of abuse and ridicule has left Michael anxious and afraid to leave the house. Now with the help of his devoted wife he must follow Dr. Now's program to keep from eating himself to death.

Shannon's husband loves her the way she is, but that may not help because she's 700 pounds and bedridden. Dr. Now knows it's not easy to break a toxic cycle of overfeeding and enabling, but that's what needs to happen if Shannon wants to live past 40.

Irene had to move back in with her son because her weight made it unbearable to live on her own. When Dr. Now can't get through to her, the only thing that might help her break the cycle is a once-in-a-lifetime turn of events.

Through tough times, food has always been Tammy's friend. But now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

Having her daughters help bathe her is not how Chrystal pictured parenting, but she is so large now that there's no other option. Chrystal wants Dr. Now's help, but she didn't know that bringing her childhood trauma to light would be part of the deal.

When Nathan's weight gets in the way of the only healthy thing in his life - his job as a drama teacher - it's a wake-up call for him. But changing his life might mean a falling out with his wife, Amber, who is also overweight, unless she can lose, too.

For Julian and his wife, Irma, it was love at first sight. But in order to grow old together, Julian will have to overcome the food addiction that made him more than 800 pounds, and Irma will have to hold on no matter how difficult the journey may become.

Bianca is all in for a move to Houston with her boyfriend and two young kids to get Dr. Now's help with a second weight-loss surgery. But just when the coast is clear, her boyfriend's change of mind could undermine her progress.

Mike was born with a talent for sports -- and an omnivorous appetite to match. After his football dreams were dashed by multiple concussions, he packed on over 700 pounds. Now he must find a new purpose in life to avoid succumbing to pain and regret.

Lacey is so big from overeating that she can barely leave the house, but that hasn't stopped her from finding love with Ricky. Her weight isn't the only thing between her and a happy husband, however, with Ricky's sister Sharon in the picture.

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only option.

Ryan moved to Montana to keep himself from going down a dark path of drug addiction. However, his new path may be no less lethal than the last if he can't find a way to curb his eating habits before they kill him.

For James B, food means family. He grew up eating rich Haitian food and loves it with a passion. Now, James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

Living on a homestead with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Margaret's life at 700 pounds is in need of a jump start. At age 35, she is a mama's girl. Now, it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister. But if he can't find a way to believe in himself, he'll never be able to stop eating.

Dolly has gotten too comfortable at 600 pounds. There's physical pain all over, and the skin apron pulling on her abdomen is miserable, but with her mom and others waiting on her hand and foot, she manages to avoid ever taking responsibility for her life.

For Larry, a second weight loss surgery would mean a second chance at a career as a gospel recording artist. But a beautiful singing voice doesn't pair well with a 600-pound eating habit. If Larry can't make the choice to change, then no one can help him.

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy. But Randy falls ill, and Lisa is about to find out if she has the will and determination she needs in order to turn her life around.

Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth. Now he weighs 800 pounds, and he's relying on his favorite foster mom to support him as he finds the motivation to change and save his own life.

As an Italian American, Geno was raised with lots of love, family and food. Now, he's still living with his mom and eating himself to death, and it's time to make a change. Geno's cousin, Nico, joins the cause, and they pledge to lose weight together.

Latonya found the man she wants to marry. The only problem is that, at almost 700 pounds, she can't walk down the aisle. Latonya doesn't want to give up the food that she's used to, but will she do it for love?

Wess gets off to a great start in Dr. Now's program, but when the cravings continue after surgery, Dr. Now sends him to therapy to confront his demons. Now, Wess must ask himself whether he is ready to live his truth as a gay man in small town Texas.

Syreeta thinks that anyone trying to help has an ulterior motive, but now she's gotten so big she desperately needs help. She's learning to let down her guard for her husband, but weight loss surgery will be tough if she can't learn to trust the surgeon.

Mark sets out with a goal for weight loss surgery, but as weight loss gets easier, he turns down medical advice and decides to do it on his own. Now, Mark thinks he can lose 500 pounds by himself, but Dr. Now sees this as another excuse not to change.

With her weight spiraling, Stephanie needs her mom's help to care for her three kids. Now, she's at the point where she'll have to lose weight or risk not having the chance to see her kids grow up.

Nothing means more to Chris than his relationship with his daughter, Zoey, but now he feels he is failing her as his weight gain begins to limit his mobility. Chris turns to his mother, whom he hasn't seen in seven years, to help get his life on track.

Patrick's weight has never been a bother -- not to him, nor to his wife, Amanda. Now, however, he's so big that it's getting in the way of his relationship with his daughter. If he wants to see her graduate high school, he'll have to reverse course.

Krystal S. has finally met the man of her dreams, but she won't let herself marry him until she can be sure that she won't become bedridden and force him into the role of caretaker.

William was always mobile and fairly athletic -- that is, until he wasn't. It's been years now since a knee injury derailed his sports career, and he's ballooned up over 600 pounds. Now, to lose weight he'll have to face up to how bad it's gotten.

Abi was struggling with his weight before a fluke accident left him mostly paralyzed. Bedbound for seven years since then and topping 700 pounds, Abi's only hope for a future with his wife is to get Dr. Now's help to lose weight and find a way to stand up.

At 58, Rose had given up on life. But for her family's sake she resolves to lose over 400 pounds no matter what it takes.

Shakyia's severe obesity worsened when she became a shut-in. Despite her sister's encouragement, meeting Dr. Now proves difficult, especially without her mother's support.

Recovering addict Charles replaces drugs with food. Morbidly obese, he needs Dr. Now but his brother enables his gluttony. Will he make the trek to Houston?

Jonathan had his dream job, and he ate himself out of it; once an EMT first responder, he rarely leaves the room; his wife works full time to pay their bills; Jonathan must break the cycle of eating if he wants to keep his wife and his life.

Krystal has never let her weight get in the way, but the truth is her weight has really started getting in the way; she has the husband of her dreams who supports her unconditionally, but she has to get weight loss surgery.

Karen has gotten so out of control with her eating that she's developed a fear of leaving the house; she needs Dr. Now's help, but can Karen ever qualify for weight loss surgery if she won't leave the house?

Gary doesn't leave the bed anymore, he has his mom and a bevy of caretakers to get him what he needs; but his life is slipping away from him; he is so overweight that just getting to Houston may be out of the question.

At 6'3 and over 700 pounds, Jacky has barely had a chance to live; she's never fit in anywhere; now that her parents have passed, she has a fresh chance to discover the world anew, but first she's got to lose 500 pounds; with bonus scenes.

Deshaun takes being protective of his mom to the next level. He's over 700 pounds and won't leave his mother's apartment. Dr. Now and Dr. Paradise might be able to get him to leave the bedroom, but will Deshaun ever make it to Houston?

Pastor Juan's love of food made him overweight, but it has never been a problem until recently, since he's gotten too big to preach and sing to his congregation. If Juan is to help others, he must first help himself by curbing his earthly appetite.