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House begins a detox program at Mayfield Psychiatric Hospital to get the Vicodin out of his system in an attempt to control his hallucinations. House plans to leave the treatment facility once he is clean, but he is strong-armed into staying by his attending physician, Dr. Darryl Nolan. Dr. Nolan agrees to write a recommendation to reinstate House’s medical license only if House agrees to further treatment. When House is moved to a new ward in the hospital, he develops a close relationship with his new roommate, Alvie, and Lydia, a frequent visitor who helps House bend the rules. House asks Alvie to help him uncover incriminating information about Dr. Nolan that would allow him to blackmail his way out of the treatment center and convinces Lydia to loan him her car to sneak out a delusional patient in an attempt by House to undermine Dr. Nolan’s course of treatment. But when devastating events ensue, House is humbled into reluctantly accepting help.House returns home to Princeton where he continues to focus on his recovery, but surprises Cuddy with the news that he’s making a big change in his life. Meanwhile, the team is unable to diagnose a loud-mouthed video game creator who posts each new symptom on the Internet and opts for treatments suggested by the online community rather than by the doctors, and Foreman angles for House’s job, but the pressure to solve the case creates tension in his relationship with Thirteen.When a controversial African politician falls ill, he is brought to Princeton Plainsboro for treatment. The team struggles with whether to help a merciless dictator being subpoenaed for crimes against humanity in his country. Meanwhile, Wilson tries to make peace with a feuding neighbor, but House’s prying exacerbates the problem.